Cytomegalovirus (CMV) and Epstein Barr virus (EBV)


The viruses of the herpes family, in particular the Epstein Barr virus (EBV), the cytomegalovirus (CMV) and the herpes simplex virus may cause serious infections after transplantation. These viruses may prove to be dangerous for patients having undergone transplantation due to the immunosuppressed status of these patients. Persons with negative test results for Epstein Barr virus and CMV before the transplantation are at highest risk. In order to detect these infections, your child must undergo frequent laboratory analyses to identify a possible infection by CMV. We use prophylactic drugs such as Cymeven® (ganciclovir) and Valcyte® (valcanciclovir) to help prevent and treat CMV after the graft. The symptoms of CMV and of the Epstein Barr virus include in particular: fever, swelling of lymph nodes, leucopenia, rash, gastrointestinal bleeding and respiratory distress. When your child has one or several of these symptoms, you must immediately notify the Centre. Sometimes, there are no or only a few symptoms of an infection with the CMV or the Epstein Barr virus, this is why your gastroenterologist must regularly order blood analyses to identify a possible presence of these viruses in your child after the graft.